U Moe Zaw Oo was born in 1969, in Yangon. He actively participated in students’ demonstrations and later nationwide uprisings in 1988 when he studied at the Rangoon Arts and Science University. Then he joined the National League for Democracy led by Daw Aung San Suu Kyi in September, 1988. He was arrested in 1990 for his involvement in political activities and released in 1999. He received a master’s degree after studying at the Chulalongkorn University in Thailand while he was in exile.

Upon return to Myanmar in 2012, he served as a deputy Chief of Staff to the office of the NLD Chairperson – Daw Aung San Suu Kyi and then became the Chief of Staff of the office in February, 2016. He received a degree from post-graduate course of international strategic studies at the Royal College of Defence Studies in London in 2017. He served as an advisor to the Union Peace Commission up to the end of 2020. He was appointed by the CRPH and the National Unity Consultative Council as a deputy minister for Foreign Affairs of the National Unity Government of Myanmar on the 16th of April, 2021.